A postdoc fellowship position is available in Dr. Xuesen Dong’s lab (http://donglab.ca). Our research focuses on the mechanisms of therapy-resistant prostate cancers and the development of therapeutics to manage the disease (representative publications PMID: 32634132, 30910347, 27180064, 31819165). Ongoing projects include
- deciphering cancer stem cell signal pathways to regulate neuroendocrine prostate cancers and
- alternative RNA to regulate therapy-resistant prostate cancer progression.
- drug development targeting Lin28 and TOP2
We are looking for multiple candidates to expand the existing projects to understand how Lin28 regulates stem cell networks to counteract therapy-induced stress and apply computer-aided drug design to develop Lin28 inhibitors. Candidates with animal handling, lentiviral manipulations, or ChIP-seq backgrounds are welcome.
Qualifications of candidates are:
- Relevant Ph.D. degree in Molecular Biology, Biochemistry or Cell Biology.
- Minimum of five years related laboratory experience.
- Demonstrated solid expertise with cell culture/transfection, western blotting, real-time PCR, and molecular cloning.
- Experience with lentivirus manipulation and animal work will be considered an asset.
- Strong problem-solving skills.
- Statistical data analysis and database management skills.
- Excellent written/verbal communication skills and organizational skills
- Demonstrated ability to work in a team environment.
Salary range: $50,000 - $60,000
To apply for this position, please forward a current CV and cover letter via e-mail with the subject line Postdoctoral Fellow, Dong Lab to xdong@prostatecentre.com
NOTE: No telephone calls or drop-in inquiries are accepted. Only those under consideration will be contacted.
Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.