Yao Zhang

 
Development of lipid nanoparticle formulations for small molecule and gene delivery
 
Why did you decide to pursue a graduate degree?

I never thought I would pursue a graduate degree! I did my BSc in Chemistry at UBC and was involved in many different research areas ranging from genetics to inorganic synthesis. However, near the end of my undergraduate degree, I became very interested in nanomedicine research as it appeared to enable the treatment of a range of diseases. The opportunity to satisfy my curiosity and to do impactful work motivated me to further pursue a graduate degree.

Why did you decide to study at UBC?

It was trivial for me to pursue graduate studies at UBC. Not only is UBC a renowned university for research excellence, but it is also a central hub for lipid nanoparticle research. Notably, the use of lipid nanoparticles for gene delivery was pioneered at UBC which led to the development of the Covid-19 mRNA vaccines.

What is it specifically, that your program offers, that attracted you?

The School of Biomedical Engineering offers me the opportunity to be involved in interdisciplinary research as I have an interest in chemistry, biophysics as well as engineering. Importantly, having the chance to participate in cutting-edge lipid nanoparticle research with Dr. Pieter Cullis and being able to combine it with Dr. Sabrina Leslie’s single-particle imaging technology is an invaluable opportunity.

What was the best surprise about UBC or life in Vancouver?

The food in Vancouver is as exceptional as UBC. Although I grew up in the Vancouver area, the scenery and moderate climate is an ideal place to live and study.

Not only is UBC a renowned university for research excellence, but it is also a central hub for lipid nanoparticle research.
 
What aspects of your life or career before now have best prepared you for your UBC graduate program?

My previous research experience in both academia and industry (through the Co-Op program) enabled me to have a fundamental understanding of basic wet lab skills. My undergraduate degree in Chemistry, although quite rigorous, provided me with the necessary foundations to carry out the interdisciplinary research that I am doing today.

What do you like to do for fun or relaxation?

When I am not doing research, I enjoy hanging out with friends, playing badminton and playing League of Legends (ARAM) on weekends.

What advice do you have for new graduate students?

You read Google reviews before going to a restaurant, so the same due diligence should be done before choosing a lab. Make sure to talk to current graduate students in your prospective lab to get a first-hand review of what you might be getting yourself into. Don’t be afraid to explore your options and be open-minded. Graduate school can be a long journey, so make sure you pick a research area and project that you are truly interested in. Most importantly, have fun in the process!

 
 
Lipid nanoparticles containing 5nm iron nanoparticles! I love nanoparticles!
 

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