Pathology and Laboratory Medicine
Experimental Pathology refers to research in any area of biomedical investigation that is relevant to human disease. Since it is necessary to understand the normal working of the system to fully define the changes associated with disease, the areas represented at UBC cover a wide range of fields and approaches. Work at all levels of biological organization is involved, from protein to lipoprotein biochemistry and molecular biology through cell and tumour biology, animal models for studies on pulmonary and cardiovascular pathophysiology and viral and bacterial infection processes, to clinical studies on human population and the AIDS epidemic.
Explore our Programs in Pathology and Laboratory Medicine
Faculty Members in Pathology and Laboratory Medicine
| Name | Research Interests |
|---|---|
| Allard, Michael | Control of energy metabolism in normal and pathologic hearts; Physiologic and Pathologic Cardiac hypertrophy; Contribution of Metabolism to myocardial dysfunction after ischemia and reperfusion, especially in the setting of cardiac hypertrophy; Cardiovascular Pathology |
| Aparicio, Samuel | Breast cancer, genome sequencing |
| Bally, Marcel Bertran | Pancreas centre |
| Bennewith, Kevin | Oncology; Molecular Pathology & Cell Biology; Cancer research; Solid tumour microenvironment; Hypoxia; Metastasis research; Pre-metastatic niche; Targeting hypoxic tumour cells in therapy; Radiation biology |
| Churg, Andrew | Lung disease |
| Cote, Helene | HIV Infection, blood research, infectious diseases |
| Daugaard, Mads | Cancer progression and metastasis; Mechanisms of carcinogenesis; Cancer Diagnosis and Detection; Cancer biology; Cancer diagnostics; Cancer therapy; Cell Signaling and Cancer; Cell Therapy of Cancer; Chemotherapy; DNA damage response pathways; glycobiology; Immunotherapy; Radiotherapy; Cell stress and Cancer; Cell stress signalling in cancer |
| Devlin, Angela | Human nutrition and dietetics; Human reproduction and development sciences; Pathology (except oral pathology); cardiovascular disease; Children; developmental programming; Diabetes; Obesity |
| Enfield, Katey | Non-coding RNA Deregulation in Lung Cancer, Pseudogene-derived lncRNAs in Cancer Regulation, Cis-Acting lncRNAs in Non-small Cell Lung Cancer, Tumor-Immune Interactions in Lung Cancer, Long Non-coding RNA Transcriptomes in Cancer |
| Gao, Zu-Hua | |
| Granville, David | Autoimmunity; Medical molecular engineering of nucleic acids and proteins; Proteases; Granzymes; Extracellular matrix; Chronic inflammation; Aging; Disease models; Autoimmune disease; Skin; Vascular biology |
| Hirsch-Reinshagen la, Veronica | |
| Huntsman, David | hereditary cancer, molecular pathology, cancer biomarkers, Pancreas centre |
| Karsan, Aly | Hematological tumours; Cancer molecular targets; Leukemia; Hematopoiesis; Genomics and epigenomics; Noncoding RNAs; Aging |
| Kizhakkedathu, Jayachandran | Medical and biomedical engineering; Pathology (except oral pathology); Biomaterials; Blood Coagulation; Cell-surface Engineering; Implants and Medical Devices; Iron Chelators; Macromolecular Therapeutics; Polymers; Proteomics Tools; Thrombosis |
| Klein Geltink, Ramon | Pathology (except oral pathology); Metabolism; Immunotherapy; Cell Signaling and Infectious and Immune Diseases; Auto-Immune Diseases; Cell Therapy of Cancer; Adoptive cellular therapy; Immunometabolism; T cell function |
| Krajden, Mel | Infectious diseases, cancer hepatitis prevention and care, human papillomavirus HPV, HIV and hepatitis C virus |
| Krystal, Gerald | Blood research, immunology, inflammation, effect of diet on cancer |
| Lam, Wan | Cancer progression; Genome biology; Epigenetics; Molecular Systems Biology; Lung Cancer; Technology Development |
| Lan, James | Kidneys and Urinary System; Histocompatibility; Immunogenetics |
| Laule, Cornelia | Medical physics; Neurosciences, biological and chemical aspects; Neurosciences, medical and physiological and health aspects; Pathology (except oral pathology); Auto-Immune Diseases; Axons; brain; Central Nervous System Inflammatory Diseases; Cerebral Atrophy; Histology; image analysis; Imaging; Inflammation; magnetic resonance imaging; Magnetic resonance spectroscopy; multiple sclerosis; myelin; Nervous System Development; Neurodegenerative diseases; Neurological diseases; Neuronal Systems; pain; Pathology; Schizophrenia; Spinal Cord Diseases; spinal cord; Spinal cord injury |
| Lockwood, William | Cancer progression and metastasis; Cancer drug development and therapeutics; Mechanisms of carcinogenesis; Cancer; drug discovery; Genetics; genomics; Immune response; Lung cancer; Oncogene signaling; Proteomics; Mouse models |
| Luo, Honglin | Basic medicine and life sciences; Viral Infections; Cardiomyopathy; Innate immunity; Central Nervous System Inflammatory Diseases; Enteroviral infection and neurodegeneration; Oncolytic virus; Protein quality control in cardiac remodeling; RNA viruses |
| Mackenzie, Ian | Alzheimer's Disease |
| Nielsen, Torsten | Clinical oncology; Pathology (except oral pathology); Biomarker development; Breast Cancer; Cancer Diagnosis and Detection; Cancer of the Musculoskeletal System; Clinical trials; Epigenomics; Experimental Therapeutics; Immuno-oncology; Tissue-based diagnostic technologies; Translational research; Genetically engineered mouse models |
| Park, Yongjin | Other basic medicine and life sciences; High dimensional data analysis; Biostatistical methods; Bioinformatics; single-cell genomics; Computational Biology; Causal inference; Bayesian machine learning |
| Perrone, Lucy | Improving health outcomes through improved diagnostic testing quality, Improving capacity through strengthening health and laboratory systems, Using effective quality improvement tools and approaches to improve diagnostic service delivery |
| Quandt, Jacqueline | Neuroinflammation in damage and repair relevant to multiple sclerosis and other nervous system disorders |
| Sadar, Marianne | Prostate Cancer; Drug development; transcriptional regulation |
| Schaeffer, David | Clinical oncology; Pathology (except oral pathology); Bioinformatics; cancer genetics; Cancer biology; Genomic rearrangements; genomics; Pancreas; Pathology; patient derived models |
| Scott, David | Pathology (except oral pathology); Cancer Genomics; Determinants of treatment failure in B-cell lymphoid cancers (lymphoma and CLL); Lymphoid Cancer; Lymphoma Biomarker; Lymphoma Tumor; Lymphoma/Leukemia Molecular Profiling; Treatment management |
| Sorensen, Poul | Childhood cancer cells, genomic science |
| Steidl, Christian | Hematological tumours; Cancer; Cancer biology; Pathology; lymphoma; tumor microenvironment; Precision Medicine; genomics |
| Takei, Fumio | Molecular immunology, cancer, cell-cell interactions |
| Verchere, Bruce | Diabetes research, pediatrics, Beta cell survival and function |
| Wang, Ying | Cardiology and circulatory sciences (including cardiovascular disease); Cell differentiation, proliferation and death; Drug discovery, design and delivery; atherosclerosis; Diabetic cardiomyopathy; Vascular biology; Spatial 'Omics'; Drug repurposing and therapeutic design; Disease modeling; Digital Pathology |
| Watson, Peter | Pathology (except oral pathology); Breast Cancer; Pathology; biomarker |
| Wellington, Cheryl Lea | Alzheimer disease; dementia; metabolism; cardiovascular system; neurodegeneration; concussion; traumatic brain injury (TBI) |
| Weng, Andrew | Molecular biology |
| Wright, Joanne | Role of inflammation in the pathogenesis of chronic obstructive pulmonary disease, airways disease in asocation with mineral dusts and fumes, pulmonary vascular disease as a consequence of cigarette smoking, respiratory |
| Yip, Stephen | Pathology (except oral pathology); Cancer Genomics/Epigenomics/Proteomics; molecular diagnostics; Neuro-oncology; Neuropathology |
